CLINICAL PRESENTATION: The patient was a 56-year-old woman with a history of hypertension and hyperlipidemia from one year ago. About two years ago, papule and PUSTULAR LESIONS emerged in the extensor area of both elbows,the LESIONS were accompanied by purulent discharge and brief itching, gradually turning into erythematous perforated indurated plaques and nodules within a month. These skin LESIONS then spread to the extensor surfaces of the knees, fingertips (painful LESIONS), scalp, and neck (Figures 1-3). The skin LESIONS appeared periodically and persisted for one month, with a two-three-month interval between each period. The patient complained of dyspnea on exertion but had no symptoms of cough, hemoptysis, weight loss, fever and chills, and night sweats. A PPD skin test was performed and returned positive,tuberculosis was also reported on a CT scan of the lungs. Furthermore, evidence in favor of tuberculosis was reported in a sample of the right axillary lymph nodes. After treatment, the LESIONS healed entirely, and only the elbow and knee scars remained...

Background: Incontinentia pigmenti (IP), also known as Bloch-Sulzberger syndrome, is a rare X-linked dominant genodermatosis that presents at the time of birth or soon after birth with cutaneous manifestation. This disorder may also affect the ectodermal tissues, such as the central nervous system, skeletal system, eyes, hair, nails, and teeth. The dermatological findings occur in four successive phases.Case report: Herein, we presented the case of a two day-old female newborn with inflammatory vesiculoPUSTULAR LESIONS on the right forearm and lower limbs, who was in a good general condition. The patient had a history of similar disease in three other members of her family, who had dental abnormalities as the most common non-cutaneous manifestation. This case report highlighted the importance of a detailed diagnostic workup for the newborns with PUSTULAR skin disease.Conclusion: IP is a rare, x-linked dominant genodermatosis with multiple organs involvement. Dermatological abnormalities are the most prominent manifestation. The diagnosis is based on the clinical findings, the presence of positive family history of skin vesiculoPUSTULAR LESIONS support the diagnosis. The skin LESIONS do not require specific treatment and prognosis depend to other organs involvement.

Subcorneal PUSTULAR Dermatosis (SCPD), also known as Sneddon-Wilkinson disease, is a rare, chronic, relapsing PUSTULAR eruption first described by Sneddon and Wilkinson 1. It occurs most commonly occurs in middle-aged or elderly women 1. The primary LESIONS are pustules that arise on normal skin or an erythematous base, classically characterized as half-PUSTULAR and half-clear flaccid blisters. Erythroderma is defined as generalized erythema and scaling involving more than 90% of the body surface area 2, 3. Among the various skin diseases that can progress to erythroderma, SCPD appears to be an exceptionally rare occurrence and, to the best of our knowledge, has not been previously reported. Here, we present a case of SCPD that progressed to erythroderma.

Generalized PUSTULAR psoriasis with hypoparathyroidism has been reported previously often as a post thyroidectomy syndrome with hypoalbuminemia and hypocalcemia. But reports on association of PUSTULAR psoriasis with idiopathic hypoparathyroidism are very rare, and almost all of them occurred in patients with known psoriasis vulgaris. We report one of the youngest cases of this association in a 17 year old girl without previous history of psoriasis which her eruption disappeared completely after the correction of hypocalcemia and remained free of eruptions until 6 months afterward. This case adds further evidence to the importance of calcium in the pathogenesis of at least some forms of psoriasis.

CoronoVac is a non-viable vaccine for severe acute respiratory syndrome coronavirus 2 (SARSCoV-2). Nowadays, there has been vaccination program for at-risk groups and older adults in Turkey. We here present 72-year-old male psoriasis patient who developed generalized PUSTULAR psoriasis flare after administration of CoronoVac. The COVID-PCR test was negative and investigations for flare etiology were all normal. He was first (to the best of our knowledge) psoriasis patient who developed an erythrodermic flare after the first dose of CoronaVac vaccine.

BACKGROUND: PUSTULAR psoriasis is a rare form of psoriasis in childhood. The prevalence of psoriasis in various parts of the world varies from 0.1% to 3% and the most frequently observed variant is the plaque type, followed by the guttate psoriasis.CASE REPORT: A 4-year-old boy with a history of repeated self-limited arthritis, onycholysis, recurrent erythematous skin, diaper rash, fever and PUSTULAR LESIONS, had several hospital admissions with no benefits. After a 2-year delay in the diagnosis, he was treated as a case of PUSTULAR psoriasis which was shown by skin biopsy.

DEAR EDITOR: PUSTULAR bacterid (PB) is a PUSTULAR disorder of the hands and/or feet. It was first described by Andrews et al. There is controversy as to whether PB is a separate disease or is a variant of psoriasis pustulosa palmaris et plantaris (PPP). Until date, the etiology of PB has not been elucidated.

Background & Aim: On time diagnosis of jaw LESIONS is important to achieve proper treatment plan by dentist, and the way to improve this aim is identifying of epidemiological, clinical and paraclinical characterization of LESIONS. Giant cell LESIONS are the group of oral and maxillary LESIONS which could be destructive. The aim of the present study was to determine the prevalence of oral giant cell LESIONS in period of 22 years in Shaheed Beheshti University Dental Faculty, Oral Pathology Department. Methods & Materials: This cross sectional and retrospective study was carried on descriptively on existing data. The study included patient's files with oral giant cell LESIONS in oral and maxillofacial pathology department in Shaheed Beheshti Dental School during 1981 till 2003. Data were analysed with Excell software by chi-square test. Results: Out of 3390 studied files in period of 22 years, 325 cases (9.5%) were giant cell LESIONS. The most prevalent lesion was peripheral giant cell granoluma (PGCG) and the prevalent ones were central giant cell granoluma, aneurysmal bone cyst, giant cell tumor and Brown tumor. Prevalence of LESIONS in female were 58.2% and 41.8% in the male. Radiolucency was the most observed radiographic view. In 44.8% of cases primary clinical diagnosis were correct. Conclusion: The prevalence of oral giant cell LESIONS was 9.5%. PGCG was the most prevalent. Calculus and dental plaque are the etiological factors of this lesion, which determines that hygienic instructions are the main components of dental performance. On the other hand, 39.3% of the discussed LESIONS had incorrect clinical diagnosis which emphasized the microscopic evaluation of biopsies for correct diagnostic process of oral giant cell LESIONS.